Postoperative T3N0M0 high differentiation of esophageal cancer, which is a malignant tumor, is a relatively more serious disease, and requires adjuvant treatment according to the pathological type and regular review. Postoperative T3N0M0 of esophageal cancer is the postoperative pathological stage, which belongs to the second stage clinically and is a relatively early stage. However, esophageal cancer is a malignant tumor, and there is a possibility of recurrence even after surgery, so it is relatively more serious. High differentiation of esophageal cancer refers to the degree of differentiation of tumor cells. The degree of differentiation determines the degree of malignancy of the tumor. Highly differentiated tumors, close to normal cells, are relatively less malignant, but still more serious than other benign diseases. Adjuvant chemotherapy should be carried out according to the pathological type of esophageal cancer after surgery. If it is squamous cancer, it can be reviewed regularly, and if the pathological type is adenocarcinoma, it needs to be carried out chemotherapy. Therefore, after surgery, esophageal cancer needs postoperative adjuvant treatment according to the stage, pathological type and so on.