After hepatocellular carcinoma interventional treatment, some patients may have recurrence as well as metastasis, including local metastasis and systemic metastasis. For patients with recurrence, the next treatment should be formulated, which needs to be based on patients’ specific conditions. If the recurrence of liver tumor is less, interventional treatment can be considered again to control the occurrence and development of tumor through embolization or combined with other aspects of treatment, such as radiofrequency ablation, anhydrous alcohol and other treatment methods. If the liver tumor has metastasized extensively, such as systemic or pulmonary metastasis, the main treatment that can be taken is internal conservative treatment and palliative treatment to improve the patient’s survival quality. Nowadays, new treatment methods have been introduced for tumor metastasis, and if it is not possible to intervene again, it can also be combined with immunotherapy and targeted drug therapy, which are most used at present, and can improve the survival quality of liver cancer patients through systemic drug therapy.