Itchy skin in the elderly, associated with dry skin, impaired barrier function, etc., can be treated with oral medications, topical medications, and daily protection. 1. Oral medication: second-generation antihistamines can be chosen to relieve itching, such as loratadine and cetirizine. 2. Topical medication: If the local oozing and erosion, you can use boric acid solution as a wet compress, and when the oozing is reduced, you can choose glucocorticoid creams, such as halometasone cream, trimethoprim cream and so on. 3. Daily protection: reduce the frequency of daily bathing, timely use of external moisturizing agents, can choose ceramides, hyaluronic acid components of moisturizing emulsion, strengthen the whole body emollient. The above drugs need to be taken under the guidance of a physician, the elderly itchy skin should go to a regular hospital, after a clear condition targeted treatment.