Tenofovir virus does not come down through the adjustment of antiviral drugs, life maintenance, regular laboratory tests to treat. 1. Adjustment of antiviral drugs: tenofovir has a very low incidence of drug resistance, and no drug-resistant viral strains have been detected in 8 years of clinical studies abroad. However, if the adefovir has been resistant before, it is likely that the efficacy of tenofovir will be reduced. Therefore, if tenofovir is resistant to the drug, it is necessary to add another antiviral drug (emtricitabine), and then also can achieve satisfactory efficacy. However, the adjustment of drugs should be carried out under the guidance of a doctor. 2. Life maintenance: if the virus does not come down, absolutely quit smoking and drinking, avoid excessively spicy and stimulating, moldy, greasy food, to ensure adequate sleep, pay attention to some of the formaldehyde of the decoration environment will also harm the liver, resulting in reduced immunity of the liver. 3. Regular laboratory tests: if the virus continues to remain unabated, the liver function should be closely examined to see if the aminotransferase increases and whether the bilirubin is abnormal, and liver function abnormalities should be promptly given to protect the liver and reduce the enzyme. The application of drugs should strictly follow the doctor’s instructions, in the process of taking medication, feel uncomfortable, should immediately stop the medication and consult a doctor. Avoid unauthorized use of drugs to cause adverse effects.