Drinking a lot of water may affect the urine protein test. If drinking a lot of water will have a certain effect on the detection of urine protein, the discharge of urine protein is not constant. Clinical examination of morning urine is mainly due to the fact that after the night precipitation, coupled with the low volume of urine at night, the concentration of urine protein is higher, which makes it easier to detect. However, if you drink a lot of water and produce too much urine, the urinary protein may be diluted, and then the detection of urinary protein is not possible, especially for people with small amounts and micro-proteinuria. Protein in the urine may be normal when a routine urine test is performed after drinking large amounts of water, but this may be a false negative. If a urine protein test is performed, it is recommended that mid-morning urine be obtained whenever possible to improve the detection rate. It is recommended that patients who need to have a urine protein test consult with their doctor about the precautions to be taken and the specimen to be taken.