24-hour urine protein quantification is a urine test that reflects kidney function by collecting all urine excreted within 24 hours, measuring the 24-hour urine volume, and quantifying the protein in the urine. The “24-hour urine volume” in the 24-hour urine protein quantification means that the first urine in the morning is expelled, and then the second urine is retained. The time of the first urine is recorded for 24 hours until the next day. Put all the urine from each of these 24 hours into a container, mix it well, and then take 100 to 200 ml from the middle and take it to the hospital for testing. Under normal conditions, the glomerular filtration membrane can only pass substances with a small molecular weight. Normal people generally have 40-80 mg of protein in their urine each day, and this level is generally undetectable with the qualitative protein test method. With certain diseases, protein leakage increases and a positive urine protein test can be performed. Therefore, the results reported by a qualitative urine protein test are rough. A 24-hour quantitative urine protein test can accurately measure the amount of protein excreted in the urine. 24-hour urine protein quantification is a reliable indicator to determine the presence or absence of kidney disease Clinically, the occurrence of kidney disease is mostly determined by a combination of qualitative and quantitative urine protein indicators in the routine urine examination. The qualitative urine protein index is often referred to as negative or positive urine protein. If the urine protein test result is positive, the degree of kidney disease depends on how many + it is. The quantitative urine protein test is a more accurate reflection of the kidney function of the patient, and the common diagnostic indicator is the 24-hour urine protein quantification. Occasionally, the 24-hour urine protein quantification exceeds the limit, but it cannot be diagnosed as kidney disease. In normal people, the 24-hour urine protein quantification range is less than 150mg/24 hours. If a person’s 24-hour urine protein quantification is above this normal reference range, he or she may be considered to have renal impairment. Although 24-hour urine protein quantification is a reliable indicator of the occurrence of kidney disease, it is inaccurate to conclude that kidney disease has occurred in a patient based on a single abnormal 24-hour urine protein quantification test result. In order to make a clinical diagnosis of kidney disease, it is usually necessary to repeat routine urine tests. By doing regular checkups, the patient can be determined to have kidney disease only if there are three or more 24-hour urine protein quantification indexes above the normal reference range. Regular checkups, early detection and treatment to prevent deterioration The early onset of kidney disease is insidious, and patients have no obvious symptoms, so it is easy to be ignored. When many people seek medical attention, kidney disease has already developed to the middle or late stage, which brings great difficulty to the treatment of kidney disease in the later stage. Therefore, it is important to develop a good habit of regular health checkups to keep an eye on your body and check for any complications of kidney disease. Some kidney diseases often require a “24-hour urine protein quantification” test, so how to collect and send urine specimens? In order to accurately measure the 24-hour urine protein quantification, the urine in the bladder should be emptied and discarded at 8:00 a.m., start timing, and store all the urine excreted for 24 hours in a container (including the urine quasi-solved at 8:00 a.m. the next day), and send it all for examination. If you have a bowel movement within the 24-hour period, you should first collect the urine and then remove it. Small volumes of urine should also not be missed. If the urine volume is not collected completely, the calculation of urine protein volume will not be accurate. Before the test, we should measure the total amount of urine in a measuring cup, then stir it well, take out a small cup to determine the amount of protein per 100 ml, and then calculate it according to the actual amount of urine, and we can calculate the amount of protein for 24 hours. In conclusion, to accurately measure the 24-hour urine protein amount, the entire day’s urine volume must be accurately collected and the test portion must be a mixture of the total urine volume in order to be representative. Because this test is to calculate the absolute value of urine protein, it has little to do with the amount of water consumed, so it is not necessary to restrict water and food intake on the day of measurement, and eating as usual will be sufficient.