The correct way to take Dapoxetine is to take it 1 to 3 hours before sexual intercourse, it is administered with at least a full glass of water, it should not be chewed or crushed but swallowed whole, it can be taken before or after a meal, and it is recommended that it be taken in accordance with the instructions for the drug or under the supervision of a physician. The drug acts on spinal reflex pathways mediated by the brainstem, possibly by inhibiting supraspinal levels and thereby inhibiting the ejaculatory reflex, and may be used to treat poor ejaculatory control and premature ejaculation in adult male patients over 18 years of age. There is a lack of data on the use of this drug in male patients over 65 years of age. Adverse reactions such as insomnia, headache, nausea, vertigo, and syncope may occur after taking the drug. When dapoxetine hydrochloride is combined with thioridazine, the blood concentration of thioridazine can be increased, which may cause serious effects on the heart, such as severe arrhythmia; when combined with monoamine oxidase inhibitors, serious reactions such as hyperthermia, tonicity, and myoclonic spasms can occur. In combination with cytochrome P450 3A4 inhibitors, it may increase its own drug concentration. The drug is prohibited to be used in combination with potent cytochrome P450 3A4 inhibitors; prohibited to be used in combination with thioridazine, monoamine oxidase inhibitors; prohibited to be used within 2 weeks of discontinuation of thioridazine, monoamine oxidase inhibitors. Contraindicated in patients with moderate to severe hepatic impairment, severe renal impairment, cardiac pathology, seizures or unstable epilepsy and hypersensitivity to the drug. Use with caution in patients with mild to moderate renal impairment or who are taking moderate cytochrome P450 3A4 inhibitors. If you need to use the drug, please under the guidance of a doctor, strictly follow the doctor’s instructions to take medication, do not self-medication.