Interphalangeal arthritis is a common surgical condition of the foot and ankle. Bunions, hammertoes, and rheumatoid arthritis can all lead to interphalangeal arthritis, resulting in pain and limited motion in the interphalangeal joint. Common clinical treatments include interphalangeal fusion, interphalangeal arthroplasty, and interphalangeal joint replacement. Although fusion can increase joint stability and relieve pain, the loss of joint motion can have a serious impact on function. The advantages of interphalangeal arthroplasty in terms of pain relief, stability, and preservation of joint motion have also been noted. Interphalangeal arthroplasty is used in patients with interphalangeal arthritis, and the technique depends on the condition of the patient’s bone, skin, and soft tissues, as well as the condition of the adjacent joint. However, with advances in medicine and improved prosthetic techniques, interphalangeal arthroplasty has become more widely recognized and promoted. Since the development of foot artificial interphalangeal joint replacement, our department has performed 50 cases of foot artificial interphalangeal joint replacement, and the prosthesis used was Swanson artificial interphalangeal joint. 44 patients were followed up, and the average follow-up time was 2.9 years. The average follow-up time was 2.9 years. Severe pain was found in 1%, moderate pain in 4%, mild pain in 28%, and no pain in 67%. The mean preoperative interphalangeal joint mobility was 38° and the mean postoperative interphalangeal joint mobility was 29°. All patients were evaluated and 100% of the patients were able to take care of themselves and had no impact on their daily life. 93% of the patients were able to perform some activities such as running and jumping. The patient satisfaction rate was 95%. Foot artificial interphalangeal joint replacement can effectively treat interphalangeal arthritis, relieve pain, and preserve joint mobility, and good results were obtained at short-term follow-up.