Poor coagulation function, need to clarify the cause of the disease, and then targeted treatment. Generally the cause of poor coagulation function is usually caused by diseases, after the appearance of poor coagulation function, first of all, we should improve the examination of coagulation function, to clarify whether it is the prolongation of APTT or PT and some other indicators of prolongation, to guide the clinical treatment. Common diseases that cause abnormal coagulation function include hemophilia, the principle of treatment is to supplement the lack of coagulation factors, so that the concentration of coagulation factors to reach the level of hemostasis. Vitamin K deficiency requires active treatment of the primary disease causing the vitamin K deficiency and, if necessary, supplementation of coagulation factors with fresh plasma as well as prothrombinogen complexes. Disseminated intravascular coagulation requires aggressive resuscitation after identifying the cause. If abnormal coagulation function is found, it is recommended to consult a doctor as soon as possible to avoid delaying the condition.