Increased urinary protein may occur during gout. If the increase is physiological, it can be seen in gout patients with stress, severe cold or heat, strong physical labor, after eating a high-protein diet, standing for a long time, etc.; if it is pathologically increased, it can be seen after gout leads to renal damage and develops into gouty nephropathy. Gout is a heterogeneous group of diseases caused by purine metabolism disorders and/or uric acid excretion disorders, which is clinically characterized by elevated serum uric acid, recurrent acute arthritis, gouty stones and joint deformities, uric acid kidney stones, glomerular, tubular, interstitial, and vascular renal lesions. For gout patients, physiological proteinuria can occur in daily life due to mental stress, severe cold or heat, strong physical labor, after eating a high-protein diet, standing for a long time, etc., which can be returned to normal after removing the triggers. At the same time with the development of gout patients, such as blood uric acid level control is not good, may damage renal function, complication of gouty nephropathy, etc., in general, there can be intermittent increase in urine protein. Therefore, it is possible to have increased urinary protein during gout. It is recommended that gout patients follow the doctor’s instructions and actively standardize the treatment to avoid delaying the condition. At the same time, patients should eat less high-purine food such as seafood, animal offal, etc., prohibit alcohol. Drink more water daily to promote uric acid discharge.