Gallbladder stones are a common disease worldwide, with an incidence rate of up to 10% or more in developed countries. In China, due to the improvement of living standards in recent years and a diet high in cholesterol and fat, the incidence of gallbladder stones in China has increased year by year, and acute cholecystitis and biliary colic caused by gallbladder stones have become common clinical conditions, often requiring surgical treatment, therefore, gallbladder stones in the choice between cholecystectomy and biliary preservation. Not only patients do not know how to choose, but also become a problem for some doctors. How to make a suitable choice between gallbladder cutting and bile preservation has become a common concern for doctors and patients. The treatment of gallbladder stones can be traced back to more than 100 years ago, the world’s first case of gallbladder stone surgery is biliary stone extraction, in 1867 the United States Dr. Bobbs for gallbladder stone patients to open the gallbladder to remove stones, no choledochoscope assistance, stone residue is difficult to avoid, resulting in the recurrence rate of this procedure up to 90%, when the high recurrence rate of gallbladder stones troubled doctors, suffering patients, until In 1882, a German surgeon performed the world’s first open cholecystectomy for a patient with biliary colic, which not only relieved the patient’s pain, but also removed the hotbed of stone growth, and cholecystectomy quickly became the “gold standard” surgery for the treatment of gallbladder stones, especially in recent years, along with the rapid spread and popularization of laparoscopic minimally invasive gallbladder removal technology. Surgeons are beginning to realize that not all gallbladders need to be removed, especially those that are functioning well, and surgeons are beginning to think about how to choose between “gallbladder removal” and “gallbladder preservation”. Removal of the gallbladder can completely cure gallbladder stones, but bile duct damage caused by gallbladder removal is a permanent pain for surgeons, the rate of medical bile duct damage caused by gallbladder removal surgery ranges from 0% to 0.6%, gallbladder removal can also cause indigestion, bloating, diarrhea, increased risk of colorectal cancer, increased chance of duodenal reflux, and increased incidence of bile duct stones after gallbladder removal. The gallbladder is an organ of the human body with important functions: the gallbladder has the function of concentrating bile and plays an important role in maintaining bile acid balance, the gallbladder has endocrine functions and can secrete immunoglobulin, the gallbladder has the function of regulating biliary pressure, and the latest research also found that patients with gallbladder stones have a reduced incidence of heart and cerebrovascular disease, and gallbladder stone preservation has the potential to preserve the gallbladder by preserving the gallbladder and preserving the gallbladder’s ability to regulate the body’s Surgeons have recognized the importance of the “presence of the gallbladder” and have begun to study the function of the gallbladder to preserve its presence. With the rapid update of medical equipment and the use of high-definition laparoscopy and cholangioscopy, biliary technology has become completely different from the times. Modern biliary technology not only allows surgeons to clearly see the entire gallbladder through the small holes in the abdominal wall through the laparoscope, but also to enter the gallbladder through the cholangioscope to see the condition of the internal gallbladder stones and the mucosa of the gallbladder, and to remove the stones through the lithotomy basket and other minimally invasive techniques. We can even remove the stones embedded in the gallbladder duct by using advanced liquid electrolysis equipment to break them up and preserve the gallbladder, and use a combination of Chinese and Western medicine to prevent the recurrence of stones. Our minimally invasive biliary stone extraction procedures include: small incision transcholangioscopic biliary stone extraction, laparoscopic assisted small incision transcholangioscopic biliary stone extraction and laparoscopic combined with cholangioscopic minimally invasive biliary stone extraction. Indications for choledocholith extraction: diagnosed with gallbladder stones by ultrasound or other imaging examinations, confirmed by 99Te, ECT or oral cholecystography with normal gallbladder function and unrevealed gallbladder, but the stones can be removed intraoperatively and the gallbladder duct is confirmed to be patent. Contraindications for biliary stone extraction: those with atrophy of the gallbladder and disappearance of the gallbladder cavity, stones in the gallbladder duct that cannot be detected by intraoperative cholangioscopy and cannot be removed, intraoperative cholangiography confirming that the obstruction cannot be released, the presence of diffuse intermural stones in the gallbladder, and gallbladder stones with cancerous lesions. Therefore, in the era of minimally invasive surgery, surgeons should not only be minimally invasive in surgery, but also minimally invasive to the patient’s organs. When operating on gallbladder stone patients, surgeons should select the most suitable biliary preservation procedure for gallstone patients with indications for biliary preservation, and preserve the functional gallbladder to achieve minimally invasive to the patient’s body and mind, so that the patient can benefit to the maximum extent.