If chest tightness is caused by angina pectoris, nitroglycerin works faster; quick-acting heart-saving pills are effective for chest tightness caused by various reasons and have milder side effects. Nitroglycerin can relax vascular smooth muscle, dilate blood vessels, prevent and quickly relieve angina caused by coronary artery disease. However, severe headache, dizziness and other discomforts may occur after taking it, and it is forbidden for patients with allergy, early myocardial infarction, severe anemia, and elevated intracranial pressure. Quick-acting heart pill can increase the blood flow of coronary artery, relieve angina pectoris, and have some effect on chest tightness and shortness of breath caused by other reasons, but the onset of effect is slower than that of nitroglycerin in relieving angina pectoris. It has not been found to have side effects, pregnant women and allergy is prohibited. Patients with chest tightness need to be diagnosed and clear the cause of the disease under the guidance of a physician to use the drug, such as after the use of the symptoms can not be relieved or the emergence of obvious discomfort, please go to the hospital in a timely manner to consult a doctor and according to the doctor’s instructions for treatment.