Taking febuxostat uric acid down may be due to bad habits, not taking the full amount of full course of treatment, taking other drugs and other factors. 1. bad habits: if patients with high uric acid continue to eat high purine food in their daily diet, such as animal offal, meat soup, seafood, etc., do not often drink water, resulting in a large amount of uric acid accumulation in the body, even if you eat febuxostat may not be able to reduce the uric acid to normal levels. Thus, the situation of eating febuxostat uric acid can not be reduced. 2. not enough to take a full course of treatment: in taking febuxostat treatment, if you do not take under the guidance of a doctor, often missed doses, small doses, or only a few days to stop taking the drug, may make febuxostat insufficient efficacy, can not play a significant role in lowering the role of uric acid. It is recommended to follow the doctor’s instructions. 3. Taking other drugs: when the patient is taking febuxostat for treatment, if at the same time to take other drugs with elevated uric acid, such as aspirin tablets, hydrochlorothiazide tablets, pyrazinamide tablets and so on. All may affect the effect of febuxostat uric acid, so that the situation of eating febuxostat uric acid can not be reduced. Patients who can’t lower their uric acid on febuxostat should go to the rheumatology and immunology department of the hospital in time to have a relevant examination, and then follow the doctor’s instructions for treatment after clarifying the cause.