Hepatitis B immune tolerance period usually has no effect on the liver. Hepatitis B immune tolerance period generally refers to the patient carries hepatitis B virus, but the virus and the body coexist peacefully, there is no obvious effect on each other, there is no obvious damage to the liver function, laboratory tests and biochemical indicators are basically in the normal. During the immune tolerance period, the hepatitis B virus enters the human body, but at this time the body’s immune system does not cause significant effects on the hepatitis B virus, and will not destroy or deal with the infected liver cells, so the hepatitis B immune tolerance period generally does not cause damage to liver function, and will not have an effect on the liver under normal circumstances. Although the hepatitis B immune tolerance period has no effect on the liver, but at this time the viral load is high, still has a certain degree of infectiousness. Therefore, patients in the tolerance period also need to pay attention to isolation to avoid infecting people in close contact. At the same time, you need to regularly review the transaminases for elevation, if the transaminases are elevated, it suggests that hepatitis B may enter the immune clearance period, which affects the liver and requires timely antiviral treatment to avoid excessive damage to liver function.