Lung adenocarcinoma stage 1A2 moderately differentiated may recur, and its 5-year recurrence rate is about 10%, which is mainly related to physical fitness, daily life and other factors. Lung adenocarcinoma belongs to a group of non-small cell carcinoma, which mainly occurs in the mucous glands of small bronchi. Usually, lung adenocarcinoma stage 1A2 moderately differentiated has certain recurrence. According to relevant authoritative data, the 5-year recurrence rate of lung adenocarcinoma stage 1A2 moderately differentiated is about 10%, but whether it will recur or not can’t be generalized, and it needs to be determined according to the specific situation. Generally, it needs to be judged according to factors such as physical fitness, daily life and treatment plan. Lung adenocarcinoma stage 1A2 belongs to early stage lung cancer, its recurrence rate is lower compared with other stages, while moderate differentiation refers to the differentiation degree of tumor cells, generally the lower the differentiation degree, the higher the malignancy degree. To sum up, patients with stage 1A2 lung adenocarcinoma with moderate differentiation need to actively cooperate with doctors for treatment, strengthen daily life management, and review on time.