Scrotal itching and peeling may be caused by fungal infection, allergy, scrotal eczema and other reasons. 1. Fungal infection: certain fungi are keratinophilic and can decompose the lipids and keratin of epidermal cells, and their metabolites can stimulate the skin, manifesting as scrotal itching, blistering, and skinning. 2. Allergy: Allergy will make the body release histamine, stimulate the skin to produce itching sensation, allergy-induced lesions will also produce peeling symptoms. 3. Scrotal eczema: Scrotal eczema can be characterized by dry, thickened and flaky skin, often accompanied by intense itching. There are many reasons that lead to scrotal itching and peeling, this situation should be timely to the hospital, clear the cause of the disease, under the guidance of the doctor symptomatic treatment, avoid unauthorized use of drugs or treatment.