Discontinuation of insulin can lead to elevated blood glucose. Insulin is a hypoglycemic hormone, which is mainly used for type 1 diabetes and type 2 diabetes that has failed to be treated with oral hypoglycemic drugs, combined with acute and chronic complications, and gestational diabetes. Discontinuation of insulin can lead to elevated blood glucose in patients, and long-term elevated blood glucose may bring about various acute and chronic complications of diabetes. For different types of diabetes, the effects of insulin discontinuation are different and are divided into the following points: 1. Type 1 diabetes, which is insulin-dependent diabetes, requires lifelong insulin treatment. Type 2 diabetes can be treated with both oral hypoglycemic drugs and insulin. type 2 diabetes patients can stop using insulin and switch to other oral hypoglycemic drugs under the guidance of a doctor. If the duration of the disease is long, the patient loses weight significantly, and the blood sugar rises significantly, it is not recommended to discontinue insulin even if the patient has type 2 diabetes. Because discontinuing insulin may induce diabetic ketoacidosis.3. In gestational diabetes, discontinuing insulin during pregnancy will lead to significant elevation of blood glucose, which will affect the growth and development of the fetus and cause adverse pregnancy outcomes. Therefore, it is not recommended for diabetic patients to discontinue insulin on their own, and the use and discontinuation of insulin needs to be done under the guidance of a doctor.