Uric acid is a metabolite of purine substances in nucleoproteins and nucleic acids and has two sources: one is from internal production and the other is from purine metabolism in food. The liver is the main production site of uric acid, and the kidney is the excretion site of uric acid, which is filtered by the glomerulus and then excreted by the renal tubules and reabsorbed by the renal tubules, so the blood uric acid concentration is affected by the glomerular filtration function and renal tubular reabsorption function. If you can strictly abstain from purine-rich food, three days to discharge exogenous uric acid interference in blood collection, elevated blood uric acid may be caused by the following reasons: 1, damage to renal tubular excretion function, resulting in reduced uric acid excretion outside the body. 2, abnormal increase in uric acid production in the body, common in primary gout caused by hereditary enzyme deficiency and a variety of blood diseases, malignant tumors due to massive cell destruction caused by secondary gout. 3.See long-term use of diuretics, anti-tuberculosis drugs, pyrazinamide, etc., which affect the function of the renal tubules and lead to reduced uric acid excretion.