If the non-invasive DNA test reveals a high risk of trisomy 21, generally speaking, the embryo will not develop normally, but it is not absolute, and needs to be further based on the amniocentesis as well as the labor and delivery diagnosis. Non-invasive DNA is through the extraction of peripheral blood of pregnant women to indirectly detect whether the chromosomal abnormality of the fetus, which belongs to the means of screening, can not 100% determine whether it is normal or not, but the accuracy rate can also reach about 98%. If the non-invasive DNA is abnormal, then further amniocentesis is needed. Amniocentesis is a prenatal diagnostic tool with a higher accuracy rate, which can determine whether the fetus has chromosomal abnormalities. If the result is the same as the non-invasive DNA test, it is recommended to consult a doctor in time, and if necessary, the pregnancy can be terminated under the guidance of the doctor.