Scleroderma is a systemic sclerosis that progresses with localized swelling, sclerosis and atrophy. The facial features are characterized by “mask-like” changes. 1. Swelling of the skin: it appears in the early stage, the skin of the face is swollen, accompanied by skin erythema, itching and other symptoms. 2. Skin sclerosis: with the development of the disease, the patient’s facial skin will become thicker and harder. It is manifested as disappearance of facial wrinkles, shrinkage of nose, narrowing of nostrils, sharpness of nose, thinning of lips and mouth, radioactive grooves around the mouth, restriction of mouth opening, shortening of tongue tie, lack of facial expression, and “mask-like” changes. 3. Skin atrophy: skin atrophy and thinning, and even subcutaneous tissue and muscle atrophy and sclerosis, close to the bone, forming a “skin and bone-like”. Scleroderma on the patient’s appearance, life and health are very big, so once found that there are precursors of scleroderma, it is recommended to go to the hospital for a full range of timely examination, early corresponding treatment, to avoid the condition continues to worsen.