Sublingual granulation may be caused by sublingual gland cyst, oral cancer, oral polyp and so on. 1. Sublingual gland cyst: Sublingual gland cyst looks like granulation tissue, and patients may think that it is granulation under the tongue, which clinically manifests as a soft and painless lump, which is a cyst produced by mucus retention due to the obstruction of the duct of the sublingual gland. It is recommended to seek medical treatment as early as possible. 2. Oral cancer: affected by poor oral hygiene, infection, tobacco, ethanol and other factors, resulting in sublingual granulation, accompanied by ulcers, local pain and other symptoms. 3. Oral polyps: Sublingual granulation may be oral polyps, which are swellings formed by elevated and limited hyperplasia in the oral mucosa, usually caused by trauma and inflammation. It is recommended that patients go to the hospital in a timely manner, under the diagnosis of the doctor, according to the patient’s specific condition performance, targeted treatment.