There is an eye disease (acute angle-closure glaucoma) that, during an acute major attack, causes systemic symptoms such as severe headache and nausea, in addition to eye pain and blindness. Many patients often visit the neurology department for severe headache and difficulty seeing, and some patients may visit the gastroenterology department for nausea, thus delaying treatment. What is glaucoma? Glaucoma is a group of diseases characterized by characteristic optic nerve atrophy and visual field defects, with pathologically elevated intraocular pressure as the main risk factor. Glaucoma is one of the major blinding eye diseases. Acute closed-angle glaucoma and how it manifests during acute attacks Acute closed-angle glaucoma is a type of glaucoma. The acute onset of glaucoma can be triggered by certain factors. The acute onset of glaucoma is characterized by a sudden loss of vision or even the inability to see the finger in front of the eye, often accompanied by ocular symptoms such as ocular pain, eye swelling and iris vision, as well as systemic symptoms such as severe headache (often on the same side as the affected eye), nausea and vomiting. What are the common causes of acute closed-angle glaucoma? The patient’s own congenital anatomical factors (such as small eyeball, shallow anterior chamber, etc.), eye trauma causing structural damage to the eye, the gradual formation of cataracts, mood swings (such as sadness, anger, mental stimulation), extreme fatigue, dim light, prolonged head-down work or playing poker, drinking large amounts of water at a time, lack of sleep, and overeating, etc. What to do if you have acute closed-angle glaucoma Acute attacks of acute closed-angle glaucoma, if not treated promptly and effectively, often result in irreversible damage to visual function and can lead to blindness within a short period of time. It is an ophthalmic emergency that requires emergency care during an acute attack. However, not all patients with acute angle-closure glaucoma will have the above-mentioned symptoms. Sometimes mild ocular and systemic symptoms may occur under certain triggers, such as mild eye pain, eye distention, blurred vision with mild headache and nausea, etc. These symptoms may resolve on their own after rest or when the triggers are removed (from dark to strong light). Repeated occurrence of the above symptoms may also cause a gradual decline in visual function. Therefore, do not be careless when the above-mentioned symptoms occur, and make sure to go to the hospital for a checkup in time, especially do not miss the eye examination, so as not to delay the treatment leading to vision loss or even blindness.