Chest tightness, shortness of breath, cough can be caused by bronchitis, asthma, cardiac insufficiency and other diseases, according to the specific conditions, can be treated with drugs. 1. Bronchitis: it can be manifested as dry cough or coughing up a lot of sputum. When accompanied by bronchospasm, chest tightness and shortness of breath can occur to varying degrees. Cough, no sputum or little sputum, dextromethorphan can be used to suppress the cough. Coughing, sputum but not easy to cough up, can be used aminoglutethimide hydrochloride expectorant. When bronchospasm occurs, asthma medicines such as aminophylline can be used. 2. Asthma: asthma often attacks in the early morning or early morning, may appear paroxysmal cough, chest tightness, wheezing and other symptoms. Inhaled glucocorticosteroid treatment, such as budesonide powder inhaler, is commonly used. If chest tightness and wheezing are serious, short-acting β2 agonists, such as terbutaline, can be given. 3. Cardiac insufficiency: such as chronic heart failure, when the increase in activity or change in position leads to increased return blood volume, it will show symptoms such as chest tightness, cough, shortness of breath, dyspnea. Heart failure can be improved with cardiotonic diuretics such as digoxin and furosemide. Chest tightness, shortness of breath, cough can also be caused by other diseases, if the symptoms are not relieved or aggravated, it is recommended to consult a doctor in time to clarify the cause of the disease and standardize the treatment under the guidance of the doctor.