Coarctation generally refers to aortic coarctation surgery, and postoperative infections should be treated with anti-infective therapy or systemic infection care. Aortic coarctation surgery is prone to complicate postoperative wound infections, in which case the wound is promptly debrided and a rational, stepwise combination of antibiotics should be initiated promptly by a specialist. Preferred empirical adequate amount of broad-spectrum antibiotics, such as third-generation cephalosporins, aminoglycosides, etc., according to drug sensitivity test timely adjustment of medication, at the same time, should be actively identified the type of infected germs. In addition to focusing on systemic application of antibiotics, it should also strengthen the aseptic consciousness of nursing staff, take good isolation precautions, strictly hand hygiene, prepare hand sanitizer and gloves exclusively for this patient, strictly disinfect invasive operations, strengthen wound observation, clean and disinfect bed linen, instruments, etc. every day, to avoid improper operation affecting the infection control. As each person’s situation is different, should promptly communicate with the doctor, and follow the doctor’s instructions for treatment.