Objective To investigate the feasibility, advantages and disadvantages of laparoscopic modified myomectomy in the treatment of uterine myometriosis. Methods Eleven patients with severe dysmenorrhea who were hospitalized from September 2004 to March 2005 were selected for laparoscopic myomectomy. Results All 11 patients successfully completed the modified myxoma resection with complete lesion removal. There were no intraoperative or postoperative complications, and the uterus returned to normal size during the follow-up ultrasound, and the dysmenorrhea symptoms were significantly improved compared with those before surgery (P < 0.0001). Conclusion Laparoscopic modified myxoma resection is less invasive, has significant improvement on dysmenorrhea, and patients recover quickly, but the operation time is longer and requires high laparoscopic operation technique for the surgeon, which can be used as a clinical reference.