1. physiological situation: men feel pain in the urethra during sex may be due to sex too often or too much strength caused by such people should pay attention to rest, moderate physical exercise, usually without special treatment. 2. Urethritis: The pain in the urethra during sex may be caused by urethritis, and the patient may also have urethral tingling, frequent urination, urinary urgency, abnormal secretions and other symptoms, the acute attack should be avoided during sex, and ceftriaxone, azithromycin, and other medicines can be used for treatment. 3. Prostatitis: prostatitis can also cause men to feel uncomfortable inside the urethra during sexual intercourse, and patients will also have fever, suprapubic area pressure feeling, urine flow thinning and other symptoms, this kind of people should pay attention to rest, can use levofloxacin, azithromycin and other drugs for treatment. All the above drugs need to pay attention to the side effects and adverse reactions of the drugs, please use the above drugs under the guidance of a doctor. There are many reasons why men feel pain inside the urethra during sex, and it is recommended to consult a doctor in time.