Why do diabetics have to amputate their limbs?

The diabetic foot is one of the most serious complications of diabetes, requiring amputation when foot ulcer infection is severe.

Patients with diabetes who have poor long-term blood glucose control can have serious complications such as peripheral neuropathy, vascular disease, and diabetic foot, with diabetic foot ulcers being a major cause of amputation.

Diabetic patients with high blood glucose levels lead to high viscosity and hypercoagulation of the blood, and endothelial cell dysfunction at the end of the limb, such as the lower limb, can lead to occlusive lesions in the arteries of the lower limb, leading to local tissue ischemia and hypoxia, impairing the immune function of white blood cells, and if stimulated by trauma or other causes, can lead to foot breakdown and infection, forming a diabetic foot ulcer.

Once a diabetic foot ulcer is formed, if the blood sugar is high for a long time and the infection is not effectively controlled, the foot ulcer will increase in size, which can lead to gangrene in severe cases, and in such cases the condition needs to be stopped by amputation treatment, otherwise it will bring more harm to the body. The only way to avoid or delay the emergence of diabetic foot and amputation is to strengthen the control of blood sugar in diabetic patients.