The redness, swelling and strange itching at the injection site of Dulaglutide may be caused by allergy to the drug, incomplete sterilization and high blood sugar. 1. Drug allergy: some patients injected with this kind of drugs may produce anaphylactic reaction, resulting in itching and redness of the skin. It is recommended to stop the injection under the guidance of the doctor, and if necessary, take oral antihistamines to reduce the anaphylactic reaction, such as chlorpheniramine maleate, diphenhydramine and so on. 2. Incomplete sterilization: To inject Dulaglutide injection, it is necessary to sterilize with alcohol first. If the skin is not sterilized or not sterilized thoroughly, the injection may cause adverse reactions, resulting in redness and swelling of the skin and itching. 3. High blood sugar: diabetic patients with high blood sugar may also experience redness, swelling and itching of the skin. Dulaglutide injection is used for the treatment of type 2 diabetes mellitus, nausea, vomiting, diarrhea, rash and erythema at the injection site may occur after injection. It is contraindicated in patients who are allergic to Dulaglutide, medullary thyroid carcinoma and other patients. After the injection of Dulaglutide Injection, if the local redness, swelling and itching are uncomfortable, you should consult a doctor as soon as possible, and under the guidance of the doctor’s treatment.