Knee fat pad hypertrophy can be treated with general treatment such as rest, avoiding excessive activities, localized hot compresses, physical therapy such as baking, medication and surgical treatment. 1. General treatment: pay attention to rest in daily life, avoid excessive activities of the knee joint, and wear knee pads if necessary. 2. Physiotherapy: local hot compresses, baking electricity, microwave and other physiotherapy are helpful to help reduce the patient’s symptoms and local edema. 3. Medication: Oral diclofenac sodium, celecoxib and other non-steroidal anti-inflammatory drugs as prescribed by the doctor can help patients relieve pain symptoms. 4. Surgery: For patients whose symptoms are severe and cannot be relieved by the above treatments, surgery can be adopted, such as arthroscopic knee fat pad excision. It is recommended that patients with enlarged fat pads in the knee go to the hospital in time for regular treatment to avoid adverse effects.