In early September 2014, an article by Dr Brian G. Durie was published on the website of the American Multiple Myeloma Foundation, and I have translated its content for the study and reference of myeloma patients. 1.First of all, get the correct diagnosis. Do the tests you need to do, such as FISH, MRI, etc. 3, choose effective and standardized initial treatment. 4.Supportive treatment is very important. 5.Discuss with your doctor whether you need a transplant or not. 6.Do regular evaluation of the efficacy. 7.Maintain and consolidate the treatment. 8.Regular monitoring of disease related indicators. 9.Whether to switch to a new treatment plan after relapse. 10. Clinical trials of new drugs.