There are no effective drugs for HPV infection, but symptoms can be improved through the use of exfoliators, topical immunomodulatory drugs and cytotoxic drugs. 1. Keratolytic agents: Commonly used drugs include retinoic acid, etc. These drugs act on the skin lesions caused by HPV infection, which can promote the renewal of epidermal cells, promote the shedding of stratum corneum cells, and improve the symptoms. 2. Local immunomodulatory drugs: commonly used drugs include imiquimod cream and interferon gel. These drugs can induce cytokines, which can play an indirect antiviral effect. 3. Cytotoxic drugs: commonly used drugs such as fluorouracil, which can inhibit RNA and DNA synthesis, have an improved effect on hyperplastic lesions caused by HPV infection, but may lead to hyperpigmentation. It is recommended that HPV-infected people seek medical treatment in time, and use medication in strict compliance with the doctor’s instructions. If medication is not effective, treatment should also be carried out by other methods.