If the scabs of mole spotting are picked off accidentally, local disinfection and topical medication can be used to promote the repair of the wound according to the healing condition. After mole spotting, due to local tissue fluid exudation, scabs will be formed in the later stage, and it is generally recommended that patients wait for them to fall off naturally and avoid picking them off by hand. If you pick off the scab accidentally and the local area has not completely healed, such as local blood oozing, you can use iodophor disinfectant to disinfect the local area to avoid infection. You can also apply erythromycin ointment and fusidic acid cream under doctor’s guidance to prevent local infection; at the same time, you can use growth factor gel to promote healing. If you accidentally pick off the scab after mole spotting, the local wound has basically healed, only local redness, generally no special treatment, usually pay attention to keep the local dry and clean, strict sunscreen can be. After mole spotting, patients should keep the skin dry, avoid the wound getting wet, and avoid touching the scabbed parts with hands. If the above situation occurs, it is recommended that the patient go to the regular medical institution for consultation and follow the prescription of medication.