Waking up in the middle of the night can not sleep is caused by many reasons, if occasionally a few days after waking up in the middle of the night is a normal phenomenon, the reason may be the recent poor mood, worry, overworked, etc., but if this situation occurs for a long time, that is, the difficulty of falling asleep after waking up, it is a manifestation of insomnia, need to pay attention to. The common reasons for the difficulty in waking up at night and falling asleep again are as follows: 1, family genetic factors: the incidence of insomnia in those with a family history of insomnia is three times higher than in those without a family history, while in women the prevalence increases gradually with age; 2, psychological factors: life, work, study environment affects emotions, too much pressure, too high expectations of sleep; 3, lifestyle factors: changes in the sleep environment or wrong sleep position 3, lifestyle factors: change in sleep environment or wrong sleep posture, taking coffee, tea or energy drinks before bedtime, some people like to do work at night, such as writing, designing, drawing, thinking about problems, or being in a state of overfullness or hunger before bedtime, which makes it difficult to go back to sleep after waking up; 4, insufficient sleep motivation: such as sleeping too much during the day or doing things unrelated to sleep in bed for a long time, such as playing cell phones, playing mahjong, playing games, reading books, etc.; 5, somatic diseases: insomnia is the clinical manifestation of certain clinical manifestations of diseases, such as depression, somatoform disorders, restless legs syndrome, pain symptoms, itching, frequent urination, bloating, breathing difficulties, etc.; in addition, hormones, stimulant-containing drugs can also lead to insomnia. To sum up, difficulty in going back to sleep after waking up is caused by a variety of complex factors, including changes in physiology, psychology, environment, drugs and other factors, but it is easy to adjust as long as the cause is found and treated for the cause.