Hormone is the first line of treatment for nephrotic syndrome, will become very fat after using hormone, need to do the following two aspects to explain: First, hormone does have such side effects, can lead to centripetal obesity, appear commonly known as full moon face, buffalo back situation, and the longer the application of hormone, the greater the chance of side effects, but when the nephrotic syndrome is cured, the hormone slowly stop, the side effects can gradually disappear Secondly, after the application of hormones, the appetite will become better and better. If you do not control your diet and continue to consume high-calorie food, your weight will definitely increase, resulting in a fat body shape.