For patients with what patients call major triple positive, the viral replication is high, but the patient has normal liver function. For this condition, the most common etiology is that the patient is infected with chronic viral hepatitis B due to vertical transmission from mother to child, and for this condition, a major triple-positive condition usually occurs. But for this kind of patients, the general patients blood test hepatitis B DNA more suggest that the virus does not replicate, and liver function, glutathione, glutamic oxalacetic aminotransferase more in the normal, then it is recommended that patients continue to observe, usually pay attention to do not drink alcohol, do not stay up late, do not strain, eat more vegetables and fruits, appropriate supplement some multiple trace elements. In some patients, if the virus replicates, but the glutamic acid and glutamic oxalacetic aminotransferase are elevated, it is recommended that the patient should be reviewed regularly. Generally not to be antiviral treatment, because at this time for patients, the virus replication is generally not good for the treatment of antiviral drugs, but if the late emergence of patients with elevated ghrelin, ghrelin, should consider taking antiviral drugs for treatment, or injection of interferon for further antiviral treatment.