The main consideration for the presence of painful cramping in the abdomen in pregnancy is the presence of pre-eclampsia, as well as the possibility of pelvic inflammatory disease, ovarian tumor, gastroenteritis, urinary tract infection and other diseases. It is usually recommended that when such symptoms occur, you should go to the hospital for examination as soon as possible to exclude the possibility of miscarriage and other diseases.1. Pre-eclampsia: especially in early pregnancy, the pain of abdominal cramping is likely to be caused by progesterone deficiency, trauma to sexual life, intense exercise and contraction of the smooth muscle of the uterus, which may be accompanied by vaginal bleeding. The diagnosis can be made through ultrasound, blood HCG and progesterone tests, and it is recommended to actively treat the fetus and rest in bed. Usually it is not difficult to diagnose with medical history and gynecological examination. It is suggested that broad-spectrum antibiotics cephalosporins or macrolides can be used for treatment; 3. Ovarian tumor: after pregnancy, the uterus increases, so the tumor is squeezed, so it will lead to abdominal cramping and pain. Preliminary diagnosis can be made through ultrasound examination, and if the tumor is relatively large, surgery can be considered. 4, gastroenteritis: inflammatory reaction in the gastrointestinal tract due to unclean diet may lead to abdominal cramping and pain, and may be accompanied by an increase in the number of stools or the phenomenon of thin stools. Through routine stool examination, combined with the clinical history, can often make a preliminary diagnosis, it is recommended to follow medical advice and medication; 5, urinary tract infection: common in urethritis, cystitis, infection may cause abdominal cramps and pain, but also accompanied by the frequency of urination, urinary urgency, urinary pain and the possibility of meatus hematuria. The diagnosis can be made through routine urine examination. It is recommended to take oral cephalosporin antibiotics for treatment, and to drink more water.