What drugs should not be used for pregnancy in patients with lupus nephritis?

  The 2012 KDIGO guidelines on glomerulonephritis issued by the US have several recommendations for pregnancy in lupus nephritis: 1. Cyclophosphamide, MMF (mycophenolate, primaquine), ACEI (e.g., lortensin, montelukast), and ARB (e.g., dyvin, coxsulas, ambrovir) are not used during pregnancy.  2. Hydroxychloroquine can continue to be used during pregnancy.  3.If a patient with lupus nephritis who is using MMF becomes pregnant, it is recommended that MMF be converted to azathioprine.  4. If a patient with lupus nephritis has a relapse during pregnancy, she can be treated with glucocorticoids or, depending on the severity of the disease, with azathioprine. Zhang Yimin, Department of Nephrology, The Sixth Hospital of Sun Yat-sen University 5. If a patient with lupus nephritis is using glucocorticoids or azathioprine, it is not necessary to reduce the dosage during pregnancy and maintain it at least until 3 months after delivery.  6. During pregnancy in patients with lupus nephritis, low doses of aspirin are recommended to reduce the risk of miscarriage.  Therefore, cyclophosphamide, MMF (mycophenolate, primaquine), ACEI (e.g. lortinexin, montelukast), ARB (e.g. dextran, coxswain, ambrovir) should not be used during pregnancy!  Glucocorticoids, hydroxychloroquine, azathioprine, and aspirin can be used!