Uterine atrophy is usually due to the low secretion of estrogen in women’s bodies, which cannot effectively promote the hyperplasia of uterine smooth muscle cells, resulting in the thinning of the myometrium and the reduction of blood flow to the uterus, which further develops into the slowing down or stopping of the proliferation and repair of the endometrial mesenchyme and glands, thus causing the uterus to atrophy and become smaller. Uterine atrophy is most often seen in postmenopausal women. After menopause, the level of estrogen decreases dramatically, and in addition to the inability to maintain normal female physiological functions, degenerative changes or diseases such as atrophic changes in the genitourinary tract, metabolic changes, cardiovascular disease, osteoporosis, and cognitive decline may gradually occur years after menopause. The atrophic changes in the genital tract are mainly manifested by the atrophy of the uterus, the inelasticity of the vulva and vagina, the atrophy of the cervix, and the smallness and hardness of the uterus that can be palpated during internal examination. This physiological change is a manifestation of long-term low estrogen levels and generally does not require treatment.