The liver is one of the most common sites for metastases, and all kinds of tumors can metastasize to the liver via blood or lymph. Most of the common liver metastases are from stomach cancer, colon cancer, rectal cancer, pancreatic cancer, lung cancer, breast cancer and so on. When metastasis occurs in the liver, it is already in the advanced stage of tumor, when there is little chance of surgical resection, and traditional intravenous chemotherapy has many side effects and poor results. Interventional therapy can achieve targeted treatment by injecting drugs directly into the tumor, together with embolization pellets that can block the tumor’s nutrient vessels to “starve” the tumor cells. Alternatively, it can be combined with ablation techniques such as radiofrequency, microwave and freezing to directly kill tumor cells. Interventional treatment is carried out under the supervision of advanced equipment, thus it has accurate positioning, precise efficacy, fast recovery, low cost and less damage to liver function. It has been accepted by the majority of patients and become the preferred treatment for liver metastases. Some patients can achieve clinical cure, and most of them can significantly prolong the survival period and quality of life after interventional treatment.