The cause of urethral burning and tingling in men is commonly due to inflammation of the urinary system, such as urethritis, prostatitis or cystitis. When the urethra burning, stinging pain need to be urine routine, prostate fluid routine and ultrasound testing of the urinary tract, according to the test results, combined with the patient’s symptoms to confirm the diagnosis. The treatment of urethral burning and stinging pain is mainly based on oral medication, including traditional Chinese medicine and Western medicine. Chinese medicine is mainly to choose the drugs that clear heat, diarrhea, detoxification, and lymphatic drainage, and commonly used Chinese medicine includes Bazheng capsule, Hot Lymphatic Qing granules or retention of urine clearing tablets, and so on. Western medicine is mainly based on the results of drug sensitivity test, choose the appropriate sensitive antibiotics for treatment.