The absence of menstruation after stopping progesterone may be caused by pregnancy, insufficient estrogen level, cervical adhesion, etc. According to the specific situation, continued observation, sequential use of estrogen and progesterone, and surgery should be given as treatments. 1. Pregnancy: After pregnancy, the level of progesterone increases, the level of estrogen increases, and the hormone level does not decrease after progesterone is stopped, resulting in the absence of menstruation. If there is a requirement for childbearing, it is necessary to continue observation and regular examination; if there is no requirement for childbearing, it is necessary to terminate the pregnancy. 2. Low estrogen level: the ovarian function of women decreases, the level of estrogen in the body decreases, the endometrium is thin, and menstruation does not occur after taking progesterone. It is necessary to give estrogen and progesterone sequential treatment, such as estradiol valerate and dydrogesterone tablets sequential oral, estradiol valerate and medroxyprogesterone acetate tablets sequential oral and so on. 3. Cervical adhesion: when the cervical adhesion, the menstrual blood can not flow out, which can cause the absence of menstruation after the discontinuation of progesterone, and it is necessary to give hysteroscopic adhesion excision, cervical dilatation, and so on. After stopping progesterone, you need to go to the regular hospital in time to find out the cause of the disease under the guidance of the doctor, and give targeted treatment.