A section of the spine that hurts when pressed is considered to be related to spondylitis, interspinous ligament strain, lumbar intervertebral disc herniation, ankylosing spondylitis, and so on. 1. Spinodontitis: the ligaments on the surface of the spinous processes may be strained due to frequent bending or hard work, resulting in localized pain. 2. Interspinous ligament strain: due to prolonged sitting or a posture for too long, causing chronic strain on the interspinous ligament, aseptic inflammation occurs, and the interspinous ligament hurts when pressed, and some of them are accompanied by lumbar spine activity limitation. 3. Lumbar disc herniation: Nucleus pulposus herniation compresses the nerves and causes lumbar pain, leg pain, leg numbness, if there is localized pain by pressing and radiating to the lower limbs, the possibility of lumbar disc herniation should also be considered. 4. Ankylosing spondylitis: aseptic inflammation of the soft tissues around the spine can cause pain at night, morning stiffness, and proper lumbar activity can get better. A section of the spine is painful when pressed, it is recommended to go to the hospital in time for examination and treatment after clarification of the cause of the disease.