Severe hair loss may be caused by androgenetic alopecia, spot baldness and other reasons, you can choose oral medication, topical medication for treatment. 1. Androgenetic alopecia: after the disease, the hair will become thin and the scalp is greasy. In this case, you can choose Finasteride tablets (for men), spironolactone tablets (for women) and other oral drugs, combined with topical Minoxidil tincture and other drugs to promote hair growth. 2. Patchy baldness: It is a kind of limited patchy baldness that occurs suddenly on the head, and there is usually no other abnormal manifestation except the absence of hair on the affected area. In this case, you can use topical minoxidil tincture, halometasone cream and other drugs, and in serious cases, you need to take oral prednisone acetate tablets and other drugs to control hair loss and promote the growth of new hair. When the hair loss is very serious, it should be noticed, timely consultation, and follow the doctor’s instructions to take medication, so as not to delay the condition.