There is no specific antidote for tetrodotoxin. If inadvertently ingested, it can be treated with propofol injection, atropine, etc. under medical supervision. Tetrodotoxin is a toxin present in the liver and ovaries of puffer fish. If inadvertently ingested, it can damage the patient’s gastrointestinal tract, nervous system, etc., resulting in muscle paralysis, respiratory distress and other symptoms. At present, there is no antidote for tetrodotoxin, and it is usually treated with gastric lavage or drugs such as propofol injection and atropine. After inadvertent ingestion of the toxin, it is necessary to seek medical treatment in time, first of all, to take emetic, gastric lavage, diarrhea and other ways to try to separate the toxin from the body, and under the guidance of the doctor to carry out drug treatment. Among them, propofol injection can treat tetrodotoxin-induced respiratory paralysis and muscle paralysis, etc. Atropine can effectively inhibit tetrodotoxin and promote its metabolism. In conclusion, there is no specific antidote for tetrodotoxin, and patients who have accidentally ingested it should be treated in time to avoid serious consequences.