Usually, New Crown vaccine can achieve a better immunization effect when the body is healthy and free of disease. Whether there is anything wrong with the New Crown vaccine during coughing needs to be determined based on the cause of the cough, the severity of the cough, and whether it is accompanied by other abnormal symptoms after vaccination. On the one hand, if the coughing symptoms of the vaccinated person are mild and are caused by chronic diseases such as chronic bronchitis and chronic obstructive pulmonary disease, the disease has been controlled and the patient is in the stable stage of the disease, paying attention to the observation after vaccination with New Crown vaccine will generally not cause significant harm to the organism, but it cannot be excluded that it may lead to the aggravation of coughing symptoms. On the other hand, if the vaccinated person is in the acute phase of respiratory disease, has a severe cough with fever, or has cough symptoms caused by allergy, the New Crown vaccination may cause or aggravate adverse reactions to the vaccine, such as hard knots, redness, swelling and pain at the injection site, or adverse reactions such as fever, headache, weakness, muscle aches, nausea, etc., and may also reduce the New crown vaccine effect. Therefore, it is recommended to avoid the vaccination during the coughing period. If a second or third dose of the vaccine is needed, postpone the vaccination until the cough has completely recovered. If you do not know the extent of your cough, you can also consult with your local vaccination site to clarify whether you can receive the vaccination. In addition, special attention should be paid to the presence of fever, i.e., axillary temperature >37.3°C, and to people who are in the acute phase of the disease, allergic to the components of the New Crown vaccine, or suffering from uncontrolled epilepsy or other serious mental illnesses.