You can take roxithromycin capsules after drinking alcohol because roxithromycin belongs to the macrolide class of drugs and does not produce a disulfiram-like reaction with alcohol. Drugs that tend to produce disulfiram-like reactions with alcohol in clinical practice include cephalosporin antibiotics and nitroimidazole antibiotics such as metronidazole and ornidazole. However, it must be noted that because roxithromycin can cause damage to the liver and drinking alcohol can also aggravate the liver burden, patients who drink alcohol for a long time may have abnormal liver function and try not to use macrolides, including roxithromycin. If you must use such drugs, test your liver function before using them and review your liver function regularly during the medication period. If liver function impairment occurs stop the medication immediately or reduce the dosage and give liver-protective medication.