The normal range of platelets is (100~300)×10^9/L. A platelet count of 366×10^9/L is high, which may be physiologic or pathologic, as follows.
1. Physiologic elevation is often seen as a result of heavy sweating, dehydration and strenuous activities.
2. Pathological increases are often seen in myeloproliferative disorders, such as myelofibrosis, essential thrombocythemia, chronic granulocytic leukemia, and so on.
As there are many factors affecting the platelet count, it is difficult to obtain accurate results in a single test, so patients are advised to monitor the changes in the value dynamically. If the platelet count is significantly elevated, it is common in primary thrombocythemia (a relatively chronic myeloproliferative disorder), and a bone marrow aspiration should be considered to confirm the diagnosis.
Disease-specific diagnosis and treatment should be directed by a physician.