Pancreatic adenocarcinoma grade 2 indicates that the cancer cells are moderately differentiated, and the specific treatment needs to be determined according to the stage of pancreatic cancer, which can be treated by surgery, chemotherapy, targeted therapy, etc. Pancreatic adenocarcinoma can be divided into grade 1, grade 2 and grade 3, which is based on the differentiation degree of cancer cells. Pancreatic adenocarcinoma can be divided into grade 1, grade 2 and grade 3 according to the differentiation degree of cancer cells. Usually, pancreatic cancer with high differentiation degree and low malignancy belongs to grade 1; pancreatic cancer with medium differentiation degree and medium malignancy belongs to grade 2; pancreatic cancer with low differentiation degree and high malignancy belongs to grade 3, and pancreatic adenocarcinoma grade 2 indicates that the tumor’s malignancy degree is medium. Early stage pancreatic cancer can be treated by surgical resection, and chemotherapy and targeted therapy are needed after surgery; while most of the middle and late stage pancreatic cancers have lost the chance of surgical treatment, and can be relieved from obstruction or compression symptoms by chemotherapy, targeted therapy, immunotherapy, and palliative surgery. In conclusion, the treatment of pancreatic cancer needs to be judged according to the condition. If pancreatic cancer is suspected or diagnosed, it is recommended to go to regular hospitals to evaluate the condition and follow the doctor’s instructions to avoid delaying the condition.