Some moles sometimes produce itching during the growth process, which is a normal physiological condition. If an allergic reaction, breakage, eczema, etc. occurs in the mole body as well as the surrounding skin, it may also lead to itching of the mole. The most worrying case of itchy moles is mutation, although the possibility is low, we must pay attention to it. 1. Allergic reaction: Occasional itching of moles may be caused by minor local skin allergy or mosquito bites, for example, the fabric of clothes is rough and the fabric fibers stimulate the moles and the surrounding skin, resulting in itching. 2. Breakage: When a mole and the surrounding skin are broken, there will be itchy feeling during the healing process. 3. Eczema: If there is eczema around the mole, the local skin will have itching symptoms and the itchiness will spread to the location of the mole; 4. Mutation: If there is no obvious trigger for itching and it lasts for too long, or if it is accompanied by enlargement, increase and oozing of the mole, there may be some mutation, and the possibility of malignant change cannot be excluded, so it is recommended to go to the hospital for examination and treatment in time. If there is an itchy mole, pay attention to care and avoid scratching the skin, and you can use anti-itch ointment. Pay attention to the growth of moles, and if excessive growth or change in nature occurs, it is recommended to consult a professional doctor for early treatment.