High 24-hour urine protein quantitative, routine urine test results are normal may be caused by diet and other physiological factors, but also may be caused by nephritis, nutcracker syndrome and other diseases. Urine routine examination is to check a random urine, random urine may be too much water to dilute the urine, and the performance of normal; 24-hour urine protein quantitative examination needs to collect 24-hour urine volume. Therefore, in comparison, the 24-hour urine protein quantitative test is more accurate than the routine urine test. 1. Physiological factors: If patients eat a lot of high-protein food or do a lot of exercise before the test, it may lead to a transient elevation of urinary protein, so the patients will have a high 24-hour urine protein quantitative, routine urine test results are normal phenomenon. 2. Nephritis: the etiology of nephritis is not clear, it is considered to be due to viral, bacterial and other pathogenic infections, autoimmune abnormalities and other etiological factors. The main symptoms of patients are proteinuria, edema, etc., so the patients will appear 24-hour urine protein quantitatively high, urine routine examination results are normal symptoms. When the patient has a high 24-hour urine protein quantitative, urine routine examination results are normal phenomenon, it is recommended that the patient should consult a doctor in a timely manner, and follow the doctor’s instructions for treatment.